| 14/09/2010 | 20:45 | Bursaspor - Valencia CF | - | |
| 14/09/2010 | 20:45 | Twente - Inter | - | |
| 14/09/2010 | 20:45 | Lyon - Schalke 04 | - | |
| 14/09/2010 | 20:45 | Werder Brême - Tottenham | - | |
| 14/09/2010 | 20:45 | FC Barcelone - Panathinaikos FC | - | |
| 14/09/2010 | 20:45 | FC Copenhague - Rubin Kazan | - | |
| 14/09/2010 | 20:45 | Manchester United - Rangers FC | - | |
| 14/09/2010 | 20:45 | SL Benfica - Hapoel Tel-Aviv | - | |
| 15/09/2010 | 20:45 | Bayern Munich - AS Roma | - | |
| 15/09/2010 | 20:45 | Marseille - Spartak Moscou | - | |
| 15/09/2010 | 20:45 | Zilina - Chelsea | - | |
| 15/09/2010 | 20:45 | CFR Cluj - FC Basel | - | |
| 15/09/2010 | 20:45 | Shakhtar Donetsk - Partizan Belgrade | - | |
| 15/09/2010 | 20:45 | AC Milan - Auxerre | - | |
| 15/09/2010 | 20:45 | Arsenal - Braga | - | |
| 15/09/2010 | 20:45 | Real Madrid - Ajax | - | |
| 28/09/2010 | 18:30 | Spartak Moscou - Zilina | - | |
| 29/09/2010 | 18:30 | Rubin Kazan - FC Barcelone | - | |
| 29/09/2010 | 20:45 | Panathinaikos FC - FC Copenhague | - | |
| 08/12/2010 | 20:45 | Bayern Munich - FC Basel | - |
| 24/08/2010 | 20:45 | Sampdoria - Werder Brême | 3-1 |
|
| 24/08/2010 | 20:45 | Sheriff Tiraspol - FC Basel | 0-3 |
|
| 24/08/2010 | 20:45 | Anderlecht - Partizan Belgrade | 2-2 |
|
| 24/08/2010 | 20:45 | Séville - Braga | 3-4 |
|
| 24/08/2010 | 20:45 | Hapoel Tel-Aviv - Red Bull Salzbourg | 1-1 |
|
| 25/08/2010 | 20:45 | Ajax - Dinamo Kiev | 2-1 |
|
| 25/08/2010 | 20:45 | Zilina - Sparta Prague | 1-0 |
|
| 25/08/2010 | 20:45 | Auxerre - Zenit St Petersbourg | 2-0 |
|
| 25/08/2010 | 20:45 | FC Copenhague - Rosenborg BK | 1-0 |
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| 25/08/2010 | 20:45 | Tottenham - Young Boys Bern | 4-0 |
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