| 28/08/2010 | 18:00 | KRC Waregem - KM Torhout | 0-2 | |
| 28/08/2010 | 19:30 | SV Oudenaarde - SK Deinze | 2-1 | |
| 29/08/2010 | 15:00 | Wielsbeke - Izegem | 1-2 | |
| 29/08/2010 | 15:00 | Coxyde - Hamme VW | 1-1 | |
| 29/08/2010 | 15:00 | SV Temse - SK Sint-Niklaas | 1-1 | |
| 29/08/2010 | 15:00 | Cappellen - SK Ronse | 0-0 | |
| 29/08/2010 | 15:00 | Eendracht Aalst - Bornem | 1-0 | |
| 29/08/2010 | 15:00 | Olsa Brakel - Geel-Meerhout | 0-1 | |
| 29/08/2010 | 16:00 | Dessel Sport - Hoogstraten | 2-0 |
| 04/09/2010 | 19:30 | KM Torhout - Dessel Sport | - | |
| 04/09/2010 | 20:00 | Hoogstraten - Olsa Brakel | - | |
| 04/09/2010 | 20:00 | SK Deinze - KRC Waregem | - | |
| 04/09/2010 | 20:00 | Geel-Meerhout - SV Temse | - | |
| 05/09/2010 | 15:00 | SK Ronse - Eendracht Aalst | - | |
| 05/09/2010 | 15:00 | Bornem - Coxyde | - | |
| 05/09/2010 | 15:00 | Hamme VW - SV Oudenaarde | - | |
| 05/09/2010 | 15:00 | SK Sint-Niklaas - Wielsbeke | - | |
| 05/09/2010 | 15:00 | Izegem - Cappellen | - |
| 1 | Eendracht Aalst | 3 | 9 |
| 2 | Geel-Meerhout | 3 | 9 |
| 3 | Coxyde | 3 | 7 |
| 4 | Dessel Sport | 3 | 6 |
| 5 | SV Oudenaarde | 3 | 6 |
| 6 | KM Torhout | 3 | 6 |
| 7 | SV Temse | 3 | 5 |
| 8 | Izegem | 3 | 4 |
| 9 | SK Ronse | 3 | 4 |
| 10 | KRC Waregem | 3 | 4 |
| 11 | Hamme VW | 3 | 4 |
| 12 | Wielsbeke | 3 | 3 |
| 13 | SK Sint-Niklaas | 3 | 2 |
| 14 | Cappellen | 3 | 2 |
| 15 | Bornem | 3 | 1 |
| 16 | Olsa Brakel | 3 | 1 |
| 17 | Hoogstraten | 3 | 1 |
| 18 | SK Deinze | 3 | 0 |
