| 06/03/2010 | 18:45 | AZ Alkmaar - Heerenveen | 4-1 |
|
| 06/03/2010 | 19:45 | ADO Den Haag - Vitesse | 1-1 |
|
| 06/03/2010 | 19:45 | Heracles - Willem II | 3-2 |
|
| 06/03/2010 | 20:45 | NAC - PSV | 2-1 |
|
| 07/03/2010 | 12:30 | Sparta Rotterdam - Ajax | 0-3 |
|
| 07/03/2010 | 12:30 | Roda JC - Feyenoord | 2-4 |
|
| 07/03/2010 | 14:30 | FC Groningen - VVV-Venlo | 1-0 |
|
| 07/03/2010 | 14:30 | Utrecht - NEC | 1-0 |
|
| 07/03/2010 | 14:30 | RKC - Twente | 0-1 |
|
| 12/03/2010 | 20:45 | Twente - ADO Den Haag | - | |
| 13/03/2010 | 18:45 | NAC - FC Groningen | - | |
| 13/03/2010 | 19:45 | VVV-Venlo - Utrecht | - | |
| 13/03/2010 | 19:45 | AZ Alkmaar - RKC | - | |
| 13/03/2010 | 20:45 | NEC - Roda JC | - | |
| 14/03/2010 | 14:30 | Feyenoord - Heracles | - | |
| 14/03/2010 | 14:30 | Willem II - Sparta Rotterdam | - | |
| 14/03/2010 | 14:30 | Vitesse - Heerenveen | - | |
| 14/03/2010 | 16:30 | Ajax - PSV | - |
| 1 | Twente | 26 | 67 |
| 2 | PSV | 26 | 65 |
| 3 | Ajax | 26 | 61 |
| 4 | Feyenoord | 26 | 50 |
| 5 | AZ Alkmaar | 26 | 42 |
| 6 | Heracles | 26 | 42 |
| 7 | Utrecht | 26 | 39 |
| 8 | NAC | 26 | 37 |
| 9 | FC Groningen | 26 | 36 |
| 10 | Roda JC | 26 | 29 |
| 11 | NEC | 26 | 28 |
| 12 | VVV-Venlo | 26 | 28 |
| 13 | Heerenveen | 26 | 26 |
| 14 | Sparta Rotterdam | 26 | 25 |
| 15 | Vitesse | 26 | 24 |
| 16 | ADO Den Haag | 26 | 23 |
| 17 | Willem II | 26 | 20 |
| 18 | RKC | 26 | 12 |
| 1 | Suarez Luis | 26 | |
| 2 | Ruiz Gonzalez Bryan | 17 | |
| 3 | Toivonen Ola | 13 | |
| 4 | El Hamdaoui Mounir | 12 | |
| 5 | Dost Bas | 11 | |
| 6 | Matavz Tim | 10 | |
| 7 | Tomasson Jon Dahl | 10 | |
| 8 | Junker Mads | 10 | |
| 9 | Vleminckx Bjorn | 9 | |
| 10 | Dzsudzsak Balazs | 9 |
